can i crush methimazole for my cat

Although not ideal, occasionally crushing methimazole or carbimazole is sometimes necessary to achieve medication. Carers should be advised to wear gloves when crushing pills since some people can be sensitive to antithyroid medications.

Possible Side Effects of Methimazole

Most methimazole side effects for hyperthyroidism appear during the first three months of treatment. When methimazole is administered to cats suffering from kidney disease, autoimmune diseases, liver disease, or other blood abnormalities, caution and/or additional monitoring are advised. Pets with methimazole allergies, as well as those with carbimazole or polyethylene glycol allergies, should not use methimazole.

The most common side effects are:

  • Not eating (anorexia)
  • Vomiting
  • Diarrhea
  • Depression
  • mild to moderate variations in the white blood cell count of your pet, which usually go away on their own

Rare side effects can include:

  • Severe facial itching
  • A decrease in blood platelet levels
  • Liver disease
  • Immune-mediated disorders
  • Decreased thyroid hormone levels can also reveal kidney disease if it is present.

Human Side Effects

Methimazole can affect the human thyroid as well. To reduce any possible drug exposure, it is advised that pet parents use gloves when giving the medication and wash their hands with soap and water afterward. When handling this medication or coming into contact with the bodily fluid of cats on methimazole, pet parents who are expecting or nursing their babies should wear gloves.


Prior to beginning methimazole treatment for hyperthyroidism in cats, thyroid function tests and complete blood counts should be performed. Following the initiation of therapy, a pet’s thyroid levels should be checked again after six weeks and three weeks. Thyroid levels should be checked every three months after the proper testing thresholds have been reached, and dosage adjustments can be made as necessary. Additional testing may be recommended by your veterinarian.

Call Your Vet If:

  • Severe side effects are seen (see above)
  • You see or suspect an overdose
  • You have more queries or worries regarding the usage of methimazole.

The above-listed adverse reactions may result from a single overdose. Serious side effects such as low platelet counts, liver disease, and changes in white blood cells can also be observed. Contact an animal poison control center or your veterinarian right away if you think there may have been an overdose. Consultation fees often apply.

Methimazole should be stored at controlled room temperatures between 68-77°F. Brief exposure to temperatures 59°-86°F are acceptable. To keep the container safe from light and moisture, keep it tightly closed.

The label of the compounding pharmacy should be followed when storing compounded medications.

Keep out of reach of children and pets.

Can methimazole for cats be crushed in soft food?

The majority of methimazole tablets are meant to be taken whole; they shouldn’t be broken up and added to food. Breaking down tablets can reveal bitter tastes and reduce the medication’s effectiveness or absorption. It is possible to crush and combine certain compounded forms of methimazole with other ingredients to make different formulations easier to administer. This is something that a compounding pharmacy can handle for specific prescriptions.

A: The most common hormone imbalance in cats, hyperthyroidism, increases with age. Excess thyroid hormone, produced by overactive thyroid glands, speeds up metabolism and causes weight loss despite increased appetite. It also causes diarrhea, regurgitation, increased drinking and urination, and behavioral abnormalities.

Q: Our 13-year-old cat, Codi, refuses to take the methimazole that he needs to treat his hyperthyroidism. I’ve attempted to crush his quarter-tablet and combine it with pilling treats and other wet foods that have been flavored with an enhancer, but to no avail. Trying to get him to take his medication is driving me crazy. Any suggestions are welcome.

Codi is receiving the generic form of methimazole from you, which inhibits the production of thyroid hormones. Felimazole, a small, smooth tablet that’s simple for cats to swallow, is another form the medication comes in.

A: Cooper was probably ill due to a germ that he wasn’t immunized against. That’s not the fault of your veterinarian because only some of the viruses and bacteria that cause kennel cough—also known as infectious tracheobronchitis or canine infectious respiratory disease complex—have vaccines available.

Radioactive iodine therapy is the only effective treatment for feline hyperthyroidism; it causes the thyroid tissue that produces too many hormones to be destroyed. Neither methimazole nor y/d is needed after treatment.


How do I get my cat to take thyroid medicine?

Pick up cat and cradle it in the crook of your left arm as if holding a baby. Position right forefinger and thumb on either side of cat’s mouth and gently apply pressure to cheeks while holding pill in right hand. As cat opens mouth, pop pill into mouth. Allow cat to close mouth and swallow.

Can methimazole for cats be given with food?

The oral form can be given with food or an empty stomach, but if your pet vomits or acts sick after receiving the medication without food, give it with food or a small treat.

Can I dissolve methimazole?

Methimazole (1-methylimidazole-2-thiol) is a white, crystalline substance that is freely soluble in water.

Why can’t I touch methimazole?

Also wear gloves when you handle broken or moistened Felimazole tablets. Methimazole, the active ingredient in Felimazole, can cause birth defects in people.