is prednisone safe for cats

Prednisone can also increase a cat’s risk of Cushing’s disease by giving them too much of the hormone. This medicine can also affect insulin and blood sugar levels in diabetic cats, making it potentially dangerous. Prednisone may also cause diabetes in cats.

What is prednisone/prednisolone?

The glucocorticoid prednisone/prednisolone (brand names: Prednis-Tab®, Deltasone®, Rayos®, Pediapred®) is used to treat a wide range of conditions in a wide range of species. Among its many applications are as an immune suppressant, an anti-inflammatory, replacement therapy for Addison’s disease, and an antineoplastic (treatment for cancer). Despite being different medications, prednisone is rapidly transformed into prednisolone in the liver, making them equally absorbed (bioequivalent).

Although certain products are designated for use in specific animal species with specific ailments, they are frequently used “off label” or “extra label” in cats, dogs, horses, small mammals, birds, and reptiles to treat neoplasia, inflammation, immune-mediated diseases, and Addison’s disease. In veterinary medicine, many drugs are frequently prescribed for off-label use. In these situations, closely adhere to your veterinarian’s instructions and warnings as they might differ greatly from those on the label.

Are there any drug interactions I should be aware of?

Amphotericin B, anticholinesterases, aspirin, barbiturates, bupropion, cholestyramine, cyclophosphamide, cyclosporine, digoxin, potassium-depleting diuretics, ephedrine, estrogens, fluroquinolones, insulin, ketoconazole, macrolide antibiotics, mitotane, mycophenolate, non-steroidal anti-inflammatory drugs (NSAIDs), phenobarbital, rifampin, vaccinations, or warfarin should be taken with caution when given in conjunction with prednisone/prednisolone.

Additionally, this product may interfere with thyroid, potassium, cholesterol, urine glucose, and allergy tests, among other laboratory tests.

Make sure your veterinarian is aware of all the medications your pet is taking, including any vitamins, supplements, or herbal remedies.

How is prednisone/prednisolone given?

Oral administration of prednisone/prednisolone comes in the form of tablets or liquid solutions. Give this medication with food. In a hospital setting, it can also be administered as an injection. Measure liquid forms carefully. Give your pet their medication in the morning for dogs and horses, and in the evening for cats, if they are on a once-daily schedule. To prevent problems, taper off this medication gradually rather than stopping it suddenly.

Unless your veterinarian advises otherwise, avoid using on pets that are scheduled for allergy testing within the next month.

This drug will start to work in about one to two hours, and clinical signs should improve after that.

FAQ

How much prednisone is safe for a cat?

The dosage of prednisone and prednisolone in cats ranges from 0.5 mg/kg to 2 mg/kg of body weight. Your veterinarian will determine the appropriate dose for your cat. Lower doses are used as an anti-inflammatory. Higher doses are immunosuppressive and have a greater risk of adverse side effects.

Why can’t cats have prednisone?

Prednisone must be metabolized by the liver before it can be used effectively. Cats are not able to absorb and convert prednisone into the active metabolite, prednisolone. This means there is a higher bioavailability of prednisolone—it is absorbed at a higher rate and degree than prednisone.

Is human prednisone the same as cat prednisone?

For many species, including dogs and humans, the two drugs are interchangeable, but cats and horses absorb prednisolone better than prednisone. The FDA (U.S. Food & Drug Administration) has approved some prednisolone products for use in dogs, cats, and horses.

Is there an alternative to prednisolone for cats?

Alternatively, dexamethasone or triamcinolone at 0.1 to 0.2mg/kg daily, then tapered to every 48 to 72 hours, can be used. Prednisone should not be used in cats, as it is not effectively metabolised to prednisolone.