can i give my cat trazodone

Trazodone is considered safe for cats, though it can lead to side effects like sleepiness or watery eyes. If veterinary visits or other anxiety-inducing situations are stressing your cat out, talk to your veterinarian about using trazodone to help your cat calm down.

About Trazodone for Cats

can i give my cat trazodone

Trazodone is classified as a serotonin antagonist (5-HT2A) reuptake inhibitor. This means it is a type of antidepressant medication.

In the US, trazodone is neither a federally scheduled nor a controlled substance. In certain jurisdictions, it is still regarded as a drug of interest that necessitates further oversight by veterinary healthcare professionals.

It is typically used to address behavioral issues and situational stress or anxiety, with a focus on shorter-term benefits. Typical feline stressors include hospital stays, car or plane travel, and veterinary clinic visits.

Although trazodone is more frequently used in dogs, studies in cats have demonstrated that it is a feasible option for cats as well.

For the long term treatment of anxiety and other behavioral disorders in dogs, trazodone may be used in conjunction with other medications. But this isn’t a typical sign that cats are using it.

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Trazodone for Cats Dosage

can i give my cat trazodone

Trazodone is not FDA-approved for use in cats. It is regarded as off-label use in cats, which is highly typical in veterinary medicine. Doses are frequently determined by research, clinical expertise, and patient responses.

In the 10-cat study from JAVMA, a dose of 50mg per cat (not 50mg per kilogram) was used 60-90 minutes prior to a veterinary visit and a generally good response was seen.

However, the optimal dosage and length of trazodone use vary greatly amongst patients. For instance, in a different study, 100 mg was used, but peak sedation didn’t happen for two hours. The cats’ behavior did not considerably improve in this study.

In another study, when used with about 100mg of gabapentin, a reduced dose of trazodone of about 25 mg, was used.

Because of this, it’s advisable to talk to your veterinarian about trazodone dosage before taking it. This is particularly relevant if your cat is currently taking additional stress or anxiety medications.

can i give my cat trazodone

Cats may be treated with the sedative and anxiety-reducing drug trazodone. It is particularly helpful for providing momentary relief from tension and anxiety associated with travel or veterinary visits. It appears to be well-tolerated in general. On the other hand, cats taking other medications, particularly those for anxiety relief, should use it with caution.

Also Read: The 7 Best Calming Cat Treats

Will trazodone put my cat to sleep?

Yes, trazodone can assist in giving cats some sedation if by “put to sleep” we mean sedation. When given at standard dosages to cats who are otherwise healthy, it rarely results in excessive sedation.


How much trazodone can I give to my cat?

The average dose is approximately 3.5 mg/lb daily. For cats of all weights, administer by mouth.

Is there a difference between human trazodone and pet trazodone?

There’s one major difference between trazodone for humans and trazodone for dogs. People can take this drug long-term. Dogs, however, should only take it for a short period of time, emphasizes Dr. Rebecca Greenstein, Veterinary Medical Advisor for Rover and Chief Veterinarian at Kleinburg Veterinary Hospital.

Can animals take human trazodone?

However, veterinarians have been using the medication off-label to relieve symptoms of stress and anxiety in dogs. These symptoms can be due to air travel, fireworks, vet visits, or separation. Trazodone has the same active ingredient for humans as it does for dogs.

How long before a vet should you give trazodone?

When used before appointments, it is given 2 hours before you travel to the vet hospital. Trazodone comes in an oral pill form and needs to be given on an empty stomach to work at its peak effectiveness. If you need to hide the pills in a small treat, that is perfectly acceptable, just not a full meal.